Imiphumela yamagagasi e-electromagnetic kuma-virus e-pathogenic kanye nezindlela ezihlobene: isibuyekezo ku-Journal of Virology

Ukutheleleka kwamagciwane ePathogenic sekuphenduke inkinga enkulu yezempilo yomphakathi emhlabeni jikelele. Amagciwane angathelela zonke izidalwa zeselula futhi angele amazinga ahlukahlukene okulimala nowonakalise, okuholela ezifweni nasekufeni. Ngokwanda kwamagciwane aphezulu we-pathogenic anjenge-acute kakhuhlane yokuphefumula i-coronavirus 2 (SARS-Cov-2), kunesidingo esiphuthumayo sokuthuthukisa izindlela ezisebenzayo neziphephile zokusebenzisa amagciwane e-pathogenic. Izindlela zendabuko zokungaphakathi kwamagciwane e-pathogenic ziyasebenza kepha zinokulinganiselwa okuthile. Ngezimpawu zamandla angenayo angenayo, ukubonwa ngokomzimba futhi akukho ukungcola, amagagasi e-electromagnetic asephenduke isu elingahle lokungasebenzi kwamagciwane e-pathogenic futhi aheha ukunakwa okwandayo. Le ndatshana ihlinzeka ngesibukezo sokushicilelwa kwakamuva ngomthelela wamagagasi we-electrogetic kumagciwane e-pathogenic kanye nezindlela zawo, kanye namathemba okusetshenziswa kwamagagasi ama-electrogenitic amagciwane e-pathogenic, kanye nemibono emisha.
Amagciwane amaningi asabalale ngokushesha, aphikelele isikhathi eside, ane-pathogenic kakhulu futhi angadala ukuba abhubha lomhlaba jikelele kanye nezingozi ezinkulu zempilo. Ukuvimbela, ukutholwa, ukuhlolwa, ukuqedwa nokwelashwa kuyizinyathelo ezibalulekile zokumisa ukusakazeka kwegciwane. Ukuqedwa okusheshayo nokusebenza kahle kwamagciwane e-pathogenic kufaka phakathi i-prophylactic, okuvikela kanye nokuqedwa komthombo. Ukungasebenzi kwamagciwane e-pathogenic ngokucekelwa phansi komzimba ukuze kuncishiswe ukuthelelekwa kwabo, i-pathogenicity kanye nomthamo wokuzala kuyindlela ephumelelayo yokuqedwa kwabo. Izindlela zendabuko, kufaka phakathi izinga lokushisa eliphakeme, amakhemikhali kanye nemisebe e-ionizing, kungangena ngempumelelo amagciwane e-pathogenic. Kodwa-ke, lezi zindlela zisenokulinganiselwa okuthile. Ngakho-ke, kusekhona isidingo esiphuthumayo sokuthuthukisa amasu amasha wokungasebenzi kwamagciwane e-pathogenic.
Ukukhishwa kwamagagasi we-electromagnetic kunezinzuzo zamandla amaningi angenayo, ukufudumala okusheshayo nokufana, ukuphikisana nama-microorganisms kanye nokukhishwa kwe-plasma, futhi kulindeleke ukuthi kube yindlela esebenzayo yokuqashwa kwamagciwane ama-pathogenic [1,2,3. Amandla amagagasi e-electromagnetic kumagciwane angenazimpawu ze-inactivate aboniswa ngekhulu leminyaka elidlule [4]. Eminyakeni yamuva nje, ukusetshenziswa kwamagagasi e-electromagnetic for ukungasebenzi kwamagciwane e-pathogenic kudonsele ukunakwa okwandayo. Lo mbhalo uxoxa ngomphumela wamagagasi e-electromagnetic kumagciwane e-pathogenic kanye nezindlela zabo, ezingasebenza njengesiqondisi esisebenzayo socwaningo oluyisisekelo nolusetshenzisiwe.
Izici ze-morphological zamagciwane zingabonisa imisebenzi efana nokusinda nokulengayo. Kuboniswe ukuthi amagagasi e-electromagnetic, ikakhulukazi imvamisa ephezulu (i-UHF) kanye ne-Ultra ephezulu imvamisa (ehf) amaza we-electromagnetic, angaphazamisa amagagasi e-morphology amagciwane.
I-Bacteriophage Ms2 (MS2) ivame ukusetshenziswa ezindaweni ezahlukahlukene zokucwaninga ezinjengokuhlaziywa kwamagciwane, ukumodela kwe-kinetic (amanzi), kanye nokubonakala kwemvelo kwama-molecule angama-viral [5, 6]. I-WU yathola ukuthi ama-microwaves ngo-2450 MHZ no-700 W kudala ukuhlanganiswa kanye nokuqothuka okubalulekile kwe-MS2 Aquatic Phushwages ngemuva kwemizuzu eyi-1] ye-Readradiation eqondile [1]. Ngemuva kophenyo oluqhubekayo, ikhefu ebusweni be-sh2 phage futhi labukwa [7]. I-KACZMARCZYK [8] iveze ukumiswa kwamasampula weCoronavirus 229E (Cov-229E) kuma-millimeter wave ngamagagasi angama-95 ghz kanye nobukhulu bamandla ka-70 kuya ku-100 w / cm2 nge-0.1 s. Izimbobo ezinkulu zingatholakala egobolondweni elinogwadule legciwane, eliholela ekulahlekelweni kokuqukethwe kwalo. Ukuchayeka kumagagasi we-electromagnetic kungalimaza amafomu amagciwane. Kodwa-ke, izinguquko ezezakhiwo ze-morphological, njengesimo, ububanzi kanye nobumbano ebushelelezi, ngemuva kokuchayeka kuleli gciwane ngemisebe ye-electromagnetic akwaziwa. Ngakho-ke, kubalulekile ukuhlaziya ubudlelwano phakathi kwezici ze-morphological kanye nezifo ezisebenzayo, ezinganikeza izinkomba ezibalulekile nezilungele ukuhlola ukuhlola igciwane elithi [1].
Isakhiwo segciwane sivame ukuqukethe i-nucleic acid yangaphakathi (RNA noma i-DNA) ne-capsid yangaphandle. Ama-acid ama-nucleic anquma izakhiwo zofuzo neziphindaphindwayo zamagciwane. I-capsid isendlalelo sangaphandle sama-subunits amaphrotheni ahlelwe njalo, okusisekelo okuyisisekelo kanye nengxenye ye-antigenic yezinhlayiya zegciwane, futhi ivikela futhi ama-acid ama-nucleic. Iningi lamagciwane linesakhiwo semvilophu esenziwe ngama-lipid nama-glycoproteins. Ngaphezu kwalokho, amaprotheni envelope anquma ukucaciswa kwama-receptors futhi asebenze njengezinti eziphambili ama-antigen amasosha omzimba angawabona. Isakhiwo esiphelele siqinisekisa ubuqotho kanye nokuqina kofuzo kwaleli gciwane.
Ucwaningo selukhombisile ukuthi amagagasi e-electromagnetic, ikakhulukazi amagagasi e-EHF electromagnetic, angalimaza i-RNA yabangenza izifo. I-Wu [1] iveze ngqo indawo enamanzi ye-MS2 iye kuma-microwaves we-MS2 kuya ku-2450 MHz Microwaves imizuzu engu-2 bese ihlaziya amaprotheni e-Capsid, ne-Cleavage Protein, ne-Replage Protein nge-Pelmerase Chain Reaction kanye ne-Reverse Reclaw Presmerase Chain Reaction kanye ne-Reverse Presmeracy Chain Reaction kanye ne-Reverse Transports POLMERerase Chain Reaction and Replace Prespand Presmerase Chain Reaction and Reprepage Presmeracture Chain Reaction kanye ne-Reversed Transpart Presmerase Chain Reaction and Replage Transports I-RT-PCR). Lezi zithobelo zakhiwa kancane kancane zabhujiswa ngokunyusa amandla amandla futhi zanyamalala ngisho nasekudaleni okuphezulu kakhulu kwamandla. Isibonelo, ukuvezwa kwamaprotheni afuywayo (934 BP) kwehliswa kakhulu ngemuva kokuchayeka kumagagasi we-electromagnetic anamandla ka-119 no-385 w futhi idatha yamandla akhombisa ukuthi amagagasi e-electromagnetic angakwazi, kuya nge-dose acid amagciwane.
Ucwaningo lwakamuva lukhombisile ukuthi umphumela wamagagasi we-electrogocnetic ku-pathogenic viral amaprotheni asuselwa ekutholeni kwabo okungaqondile okushisayo kuma-medriator kanye nomphumela wawo ongaqondile ekubhujisweni kwamaprotheni ngenxa yokubhujiswa kwama-acid acide [1, 3, 8, 9]. Kodwa-ke, imiphumela ye-Athermic nayo ingashintsha ubumbano noma ukwakheka kwamaprotheni amagciwane [1, 10, 11]. Umphumela oqondile wamagagasi we-electromagnetic kumaprotheni ama-protein ayisisekelo afana namaprotheni e-capsid, amaprotheni emvilophu noma amaprotheni we-spike amagciwane e-pathogenic asadinga ukufundwa okwengeziwe. Kusanda kuphakanyiswa ukuthi imizuzu emi-2 yemisebe ye-electromagnetic imvamisa ka-2.45 ghz ngamandla angama-700 w angaxhumana nezingxenyana ezihlukile zezinkomo zamaprotheni kanye nezinkundla zikagesi ezi-12].
Imvilovilo yegciwane le-pathogenic ihlobene kakhulu nekhono layo lokutheleleka noma lokudala izifo. Ucwaningo oluningi luye lwabika ukuthi amagagasi e-UHF ne-Electromave aclectromagnetic angabhubhisa amagobolondo e-virus ebangela izifo. Njengoba kushiwo ngenhla, izimbobo ezihlukile zingatholakala emvilophini yegciwane e-coronavirus 229e ngemuva kokuchayeka kwesibili ku-95 ghz millimeter wave endaweni yamandla ka-70 kuya ku-100 w / cm2 [8]. Umphumela wokudluliselwa kwamandla okuvuselela amagagasi kagesi kungadala ingcindezi eyanele ukuba ichithe ukwakheka kwemvilophu yegciwane. Amagciwane ambozwayo, ngemuva kokuqhekeka kwemvilophu, ukusetshenziswa kwemali noma umsebenzi othile kuvame ukwehla noma alahlekelwe ngokuphelele [13, 14]. I-Virus yegciwane le-H3N2 (H3N2) ne-H3N1 (H1N1) umkhuhlane virus kuma-8.35 GHZ, 320 W / M² no-7 GHZ, 308 W / M², ngokulandelana, imizuzu eyi-15. Ukuqhathanisa amasignali we-RNA amagciwane e-pathogenic avezwe amagagasi we-electromagnetic kanye nemodeli ehlukanisiwe eqandisiwe futhi ancishiswe ngokushesha ku-nitrogen ewuketshezi ngemijikelezo eminingana, kwenziwa i-RT-PRC. Imiphumela ikhombisile ukuthi amasignali we-RNA amamodeli amabili aguquguquki kakhulu. Le miphumela ikhombisa ukuthi ukwakheka kwegciwane kuyaphazamiseka futhi isakhiwo semvilophu sibhujiswa ngemuva kokuchayeka ngemisebe ye-microwave.
Umsebenzi wegciwane ungabonakala ngekhono lawo lokutheleleka, ukuphindaphinda futhi ubhale. Ukutheleleka kwegciwane noma umsebenzi ovame ukuhlolwa ngokulinganisa amagciwane ama-timor asebenzisa ama-plaque ass, amasiko amathimba wesiko Median infosector umthamo (TCID50), noma umsebenzi wohlobo lwentatheli yeLuciferase) Kepha futhi ingahlolwa ngokuqondile ngokuhlukanisa i-virus ebukhoma noma ngokuhlaziya i-antigen yegciwane, i-viral Particle density, ukusinda kwegciwane, njll.
Kubikwe ukuthi amagagasi e-ehf, ama-shf kanye ne-ehf ehmagnetic angena ngokuqondile anactivate aerosols noma amagciwane anamanzi. I-Wu [1] I-bacteriophage aerosol ekhiqizwe ne-neebulizer elenziwe nge-electrotorance kumagagasi e-electromagnetic ngemvamisa ka-2450 mhz kanye nama-bacteriophage ukusinda kwezinga ama-700. Ifana ne-MS2 Viral Aerosol, ama-91.3% ama-MS2 angenamikhono angenakungasebenzi ngemizuzu engu-1.5 ngemuva kokuchayeka umthamo ofanayo wamagagasi we-electromagnetic. Ngaphezu kwalokho, amandla emisebe ye-electromagnetic ukuvumela i-rus ye-MS2 yahambelana kahle nobuningi bamandla nesikhathi sokuvezwa. Kodwa-ke, lapho ukusebenza kahle kwe-decictivation kufinyelela inani layo eliphezulu, ukusebenza kahle kwe-deactivation akunakuthuthukiswa ngokwandisa isikhathi sokuvezwa noma ukukhulisa ubungako bamandla. Isibonelo, igciwane le-MS2 lalinezinga elincane lokusinda elingu-2.65% laya ku-4.37% ngemuva kokuchayeka kumagagasi angama-2450 mhz kanye namagagasi angama-700 atholakala ngesikhathi sokuvezwa okwandayo. I-Siddharta [3] i-insadiated ukumiswa kwesiko leseli eliqukethe i-hepatitis C virus (HCV) / I-HIV vimbela ukudluliswa kwaleli gciwane noma ngabe kuvezwa ndawonye. Lapho i-irrading i-HCV cell Culte Culte kanye nokumiswa kwe-HIV namagagasi aphezulu we-electromagnetic anemvamisa ka-2450 MHZ, 90 W noma ngo-180 W, akwashintsha umsebenzi wethempeli le-Luciferase, kanye noshintsho olukhulu ekufezekisweni kwegciwane. Ku-600 no-800 w for umzuzu 1
UKaczmarczyk [8] okokuqala wakhombisa ubungozi bamagagasi e-EHF ka-Ehf ngokumelene namanzi angama-2021. Badalula amasampula e-coronavirus 229e noma i-poliovirus (PV) kumagagasi angu-70 kuya ku-100 w / cm2 ngemizuzwana emi-2. Ukusebenza kahle kwamagciwane amabili ama-pathogenic kwakungu-99.98% no-99.375%, ngokulandelana. Okubonisa ukuthi amagagasi we-EHF we-EHF anamathemba okufaka isicelo abanzi emkhakheni we-virus acccactivation.
Ukusebenza ngempumelelo kwe-UHF Ukungasebenzi kwamagciwane sekuhlolwe nemidiya ehlukahlukene njengobisi lwebele nezinye izinto ezisetshenziswa kakhulu ekhaya. Abaphenyi badalule imaski ye-anesthesia engcoliswe nge-adenovirus (Adv), uhlobo lwe-poliovirus 1 (PV-1), i-Herpesvirus 1 (Hv-1) kanye ne-rhinovirus (i-RHV) ebhejane ngama-2450 mhz kanye namandla ama-720. Babike ukuthi izivivinyo ze-ADV kanye ne-PV-1 ama-antigences zaba nemibi, futhi i-HV-1, PIV-3-3, kanye ne-HRV titwors yehle ku-zero, okukhombisa ukungasebenzi ngokuphelele kwawo wonke amagciwane ngemuva kokuvezwa kwamagciwane [16, 16]. U-Elhafi [17] uveze ngokuqondile ama-swab atheleleke ngegciwane le-Avian athettic Bronchitis virus (IBV), i-Avian Pneumovirus (APV), ne-NDV) VIRUS VIRUS (AIV) kuya ku-Of 24 nd. Oven. ulahlekelwe yimithwalo yawo. Phakathi kwazo, i-APV ne-IBV kutholwe ngokungeziwe kumasiko ezinhlangothini ze-tracheal ezitholwe emibunjeni yenkukhu yesizukulwane sesi-5. Yize leli gciwane lingakwazi ukwahlukaniswa, i-viral nucleic acid isatholwa yi-RT-PCR. UBen-Shoshan [18] waveza ngokuqondile ama-2450 MHZ, amagagasi angama-750 amagagasi ka-Electromagnetic kuya ku-15 cytomegalovirus (CMV) amasampula obisi obisi abe amabele amasekhondi angama-30. Ukutholwa kwe-Antigen nguShell-Vial wakhombisa ukungasebenzi okuphelele kwe-CMV. Kodwa-ke, ngo-500 W, amasampula angu-2 kwezingu-15 awafinyelelanga ukungenelela okuphelele, okubonisa ukuhlangana okuhle phakathi kokusebenza kahle kwamagagasi ama-electromagnetic.
Kubalulekile futhi ukuthi ukubheka ukuthi i-yang [13] yabikezela imvamisa ye-resonant phakathi kwamagagasi e-electromagnetic namagciwane asuselwa kumamodeli asemzimbeni asunguliwe. Ukumiswa kwezinhlayiya zegciwane le-H3N2 nge-7.5 × 1014 m-3, ekhiqizwa yi-madin darby inja yezinso amangqamuzana (MDCK), ivezwe ngqo kumagagasi we-electromagnetic emcimbini we-820 w / m² imizuzu engu-15. Izinga lokungasebenzi kwegciwane le-H3N2 lifinyelela ku-100%. Kodwa-ke, embundwini wethiyori ka-82 W / M2, ama-38% kuphela wegciwane le-H3N2 elalingenakubekwa, eliphakamisa ukuthi ukusebenza kahle kwe-Em-Mediated Angactivation kuhlobene kakhulu nobuningi bamandla. Ngokusekelwe kulolu cwaningo, iBarbara [14] ibale ububanzi obuvame kakhulu (8.5-20 ghz) phakathi kwamagagasi e-electromagnetic kanye ne-adventity ka-14.5 ± 1 w / m2 cishe imizuzu eyi-15 kuzoholela ku-100% Ukungasebenzi. Ucwaningo lwakamuva olwenziwe nguWang [19] lukhombise ukuthi imvamisa emibi ye-SARS-Cov-2 ayi-4 no-7.5hz, eqinisekisa ubukhona bokubakhona kwama-resency amele nge-virus titer.
Ekuphetheni, singasho ukuthi amagagasi we-electromagnetic angathinta ama-aerosol kanye nokumiswa, kanye nomsebenzi wamagciwane ezindaweni eziphezulu. Kwatholakala ukuthi ukusebenza kwe-Intactivation kuhlobene kakhulu nemvamisa namandla amagagasi e-electromagnetic kanye ne-medium esetshenziselwa ukukhula kwegciwane. Ngaphezu kwalokho, imvamisa ye-electromagnetic kususelwa ekubumbeni ngokomzimba kubaluleke kakhulu e-virus activation [2, 13]. Kuze kube manje, umphumela wamagagasi we-electromagnetic emsebenzini wama-pathogenic virus agxile kakhulu ekushintsheni ukusetshenziswa. Ngenxa yendlela eyinkimbinkimbi, izifundo eziningana zibike umphumela wamagagasi we-electromagnetic ekuphindweni kabusha kanye nokubhaliwe kwamagciwane e-pathogenic.
Izindlela ezisetshenziswa yi-electromagnetic amagagasi ahlobene kakhulu nohlobo lwegciwane, imvamisa namandla amagagasi e-electromagnetic, kanye nemvelo yokukhula kwegciwane, kepha zihlala zingafakwanga kakhulu. Ucwaningo lwakamuva lugxile ezimweni zokudluliswa kwamandla okushisayo, athermal, kanye nokwakheka kwamandla.
Umphumela we-thermal uyaqondakala njengokwanda kwezinga lokushisa elibangelwa ukujikeleza okusheshayo, ukushayisana kanye nokungqubuzana kwama-molecule we-polar ezicutshini ngaphansi kwamagagasi e-electromagnetic. Ngenxa yale mpahla, amagagasi we-electromagnetic angavusa amazinga okushisa aleli gciwane ngaphezulu komkhawulo wokubekezelelwa komzimba, okwenza ukufa kwegciwane. Kodwa-ke, amagciwane aqukethe ama-molecule ambalwa we-polar, abonisa ukuthi imiphumela eqondile eshisayo ngamagciwane ayivamile [1]. Ngokuphambene nalokho, kunama-molecule amaningi we-polar aphakathi nendawo nasendaweni ephakeme, efana nama-molecule wamanzi, ahamba ngokuhambisana nenkambu kagesi ephephile ngamagagasi e-electromagnetic, akhiqiza ukushisa ngokufuya. Ukushisa kuhanjiswa ku-virus ukukhulisa amazinga okushisa awo. Lapho umkhawulo wokubekezelela usudlulile, ama-nucleic acid namaprotheni abhujiswa, okugcina kunciphisa ukutheleleka futhi akwenzile leli gciwane.
Amaqembu amaningana abike ukuthi amagagasi e-electromagnetic anganciphisa ukutheleleka kwamagciwane ngokusebenzisa ukuvezwa okushisayo [1, 3, 8]. I-KACZMARCZYK [8] iveze ukumiswa kukaCoronavirus 229E kumagagasi e-electromavirus ngamagagasi e-electromagnetic emcimbini we-95 GHZ ngokuqina kwamandla ka-70 kuya ku-100 w / cm² ngo-0.2-0.7 s. Imiphumela ikhombisile ukuthi ukwanda kokushisa kwe-100 ° C phakathi kwale nqubo kufake isandla ekubhujisweni kwegciwane le-morphology kanye nomsebenzi wegciwane. Le miphumela eshisayo ingachazwa ngesenzo samagagasi e-electromagnetic kuma-molecule wamanzi azungezile. I-Siddharta [3] I-Irradiated Cell Culture Custiction Culture yama-genotypes ahlukene, kufaka phakathi i-GT1A, GT2A, GT3A, i-GT6A, i-GT7A, nama-60 W, 360 W kanye ne-800 TUE ngokunyuka kwamazinga okushisa we Isiko leselula eliphakathi kuka-26 ° C kuya ku-92 ° C, imisebe ye-electromagnetic yanciphisa ukuthelelekwa kwegciwane noma ifakwe ngokuphelele leli gciwane. Kepha i-HCV yadalulwa kumagagasi we-electromagnetic okwesikhashana emandleni aphansi (ama-90 noma ama-180 w, imizuzu emi-3) noma amandla aphezulu (imizuzu engama-600)
Imiphumela engenhla ikhombisa ukuthi umphumela wokushisa wamagagasi we-electromagnetic uyinto ebalulekile ethonya ubuthi be-antathitha noma umsebenzi wamagciwane e-pathogenic. Ngaphezu kwalokho, izifundo eziningi zikhombisile ukuthi umphumela wokushisa wemisebe ye-electromagnetic activatiative ake amandla e-pathogenic ngempumelelo kune-UV-C kanye nokushisa [8, 20, 21, 22, 23, 24].
Ngaphezu kwemiphumela eshisayo, amagagasi we-electromagnetic angashintsha nobumbano lwama-molecule anjengamaprotheni ama-microbial nama-nucleic acid, okwenza ama-molecule ajikeleze aphindwe futhi adale, okuholela ekufeni okuncishisiwe noma okungu-10]. Kukholakala ukuthi ukushintshwa okusheshayo kwenhlekelele yamagagasi e-electromagnetic kubangela ukubambelela kwamaphrotheni, okuholela ekusonteni nasekuqothulweni kwesakhiwo samaprotheni futhi, ekugcineni, ekuboniseni amaprotheni [11] [11].
Umphumela we-Electromagnetic Waves ku-Virus Intactivation uhlala empikiswano, kepha izifundo eziningi zikhombise imiphumela emihle [1, 25]. Njengoba sishilo ngenhla, amagagasi we-electromagnetic angangena ngqo kwiphrotheni yemvilophu yegciwane le-MS2 futhi abhubhise i-acid ye-nucleic yegciwane. Ngaphezu kwalokho, ama-virus aerosols we-MS2 azwela kakhulu amagagasi e-electromagnetic kune-MS2 yamanzi. Ngenxa yama-molecule amancane ama-polar, njengama-molecule wamanzi, emvelweni ezungeze amagciwane e-MS2 arerosols, imiphumela ye-Athermic ingadlala indima ebalulekile e-Electromagnetic Wave-Wave-Medical-Medical-Mediated Acticution [1].
Umcimbi wokuphindisela ubhekisela ekuthambekeni kohlelo lomzimba lokudonsa amandla amaningi endaweni yalo ngokuvama kwemvelo kanye ne-wavelength. I-resonance yenzeka ezindaweni eziningi ngokwemvelo. Kuyaziwa ukuthi ama-virus ahlangana nama-microwaves amele kaningi kumodi ekhawulelwe ye-acoustic dipole, puromance ntomon [2, 13, 26]. Izinhlobo ze-resonant zokuxhumana phakathi kwegagasi le-electromagnetic negciwane liheha ukunakwa okwengeziwe. Umphumela wokudluliselwa kwamandla okuhambisa amandla afanelekile (i-SRET) kusuka kumagagasi we-electromagnetic ukuvala ama-acoustic oscillations (ama-virus) kumagciwane angaholela ekuphumeni kolwelwesi lwegciwane ngenxa yokudlidliza okuyi-core-capsid. Ngaphezu kwalokho, ukusebenza kwe-SRET okuphelele kuhlobene nohlobo lwemvelo, lapho usayizi kanye no-ph lwe-viral nxazonke inqume imvamisa ye-resonant kanye nokutholwa kwamandla, ngokulandelana [2, 13, 13, 19].
Umphumela wezezimali we-Electromance wamagagasi we-electromagnetic udlala indima ebalulekile ekungeneni kwamagciwane ambozwayo, azungezwe ulwelwesi lwe-bilayer eshumeke emaprotheni amagciwane. Abaphenyi bathola ukuthi ukwenziwa kwe-H3N2 ngamagagasi e-electromagnetic ngemvamisa ye-6 GHZ kanye nobuningi bamandla ka-486 w / m² bekubangelwa ukuqhekeka kwegobolondo ngenxa yethondo lokubumba [13]. Izinga lokushisa lokumiswa kwe-H3N2 likhuphuke nge-7 ° C kuphela ngemuva kwemizuzu engu-15 yokuvezwa, noma kunjalo, ngokungenwa yigciwane le-H3N2 lomuntu ngokushisa okushisayo, izinga lokushisa elingenhla kwama-55 ° C liyadingeka [9]. Kubhekwe izehlakalo ezifanayo ngamagciwane anjenge-SARS-Cov-2 ne-H3N1 [13, 14]. Ngaphezu kwalokho, ukungasebenzi kwamagciwane ngamagagasi e-electromagnetic akuholeli ekuwohlokeni kwe-viral gena genomes [1,13,14]. Ngakho-ke, ukungasebenzi kwegciwane le-H3N2 kwagqugquzelwa ukubonwa ngokomzimba kunokuvezwa okushisayo [13].
Uma kuqhathaniswa nomphumela we-thermal wamagagasi we-electromagnetic, ukungasebenzi kwamagciwane ngokubuyiselwa komzimba kudinga ama-ramather aphansi wedosi, angaphansi kwamazinga okuphepha we-microwave asungulwe yi-Institute of Electrical and Electronics Onjiniyela (ieee) [2, 13]. Imvamisa ye-resonant kanye nethamo lamandla kuncike kwizakhiwo ezibonakalayo zegciwane, njengosayizi wezinhlayiyana kanye nokuqina, futhi wonke amagciwane ngaphakathi imvamisa ye-resonant angabhekiswa ngempumelelo yokungasebenzi. Ngenxa yezinga eliphakeme lokungena, ukungabikho kwemisebe e-ionizizization, nokuphepha okuhle, i-ackoctivation enhle, i-ackoctivation yegciwane elaliwa ngumphumela we-Athermic we-CPET ethembisa ukwelashwa kwezifo zabantu [14, 26].
Kususelwa ekusetshenzisweni kwe-accocsetion yamagciwane esigabeni se-liquid nangaphezulu kwemidiya ehlukahlukene, amagagasi e-electromagnetic angabhekana ngempumelelo negciwane le-aerosol [1, 26], okubaluleke kakhulu ukulawula ukudluliswa kwegciwane emphakathini. umqedazwe. Ngaphezu kwalokho, ukutholwa kwezindawo zokuphindaphinda kwemvelo zamagagasi e-electromagnetic kubaluleke kakhulu kulo mkhakha. Inqobo nje uma imvamisa evumayo ye-vironant ethile kanye namagagasi e-electromagnetic ayaziwa, wonke ama-virus ngaphakathi kwemvamisa yemvamisa yesilonda angabhekiswa kuzo, angeke atholakale ngezindlela ze-virus zendabuko zokungasebenzi. I-Electromagnetic Angactivation of virus ucwaningo oluthembisayo ocwaningweni olukhulu nenani elisetshenzisiwe kanye nenani elinamandla.
Uma kuqhathaniswa nobuchwepheshe bokubulala bendabuko kwegciwane, amaza we-electromagnetic anezici zokuvikelwa kwezemvelo okulula, okusebenzayo, okusebenzayo lapho kubulala amagciwane ngenxa yezakhiwo zawo ezihlukile zenyama [2, 13]. Kodwa-ke, izinkinga eziningi zihlala. Okokuqala, ulwazi lwanamuhla lukhawulelwe ezakhiweni ezibonakalayo zamaza we-electromagnetic, kanye nendlela yokusetshenziswa kwamandla ngesikhathi sokukhishwa kwamagagasi we-electromagnetic adalulwa [10, 27]. Ama-Microwaves, okubandakanya amagagasi ama-millimeter, asetshenziswa kabanzi ukutadisha i-virus activation kanye nezindlela zawo, noma kunjalo, izifundo zamagagasi e-electromagnetic kwamanye amazwe, ikakhulukazi kuma-300 thz kuya ku-10 thz, angabikwa. Okwesibili, indlela yokubulala amagciwane e-pathogenic ngamagagasi e-electromagnetic awakacaciswanga, futhi amagciwane anama-spherical kuphela futhi anonduku afundwe [2]. Ngaphezu kwalokho, izinhlayiya zegciwane zincane, zingenamaselula, ziyaguquka kalula, futhi zisakazeka ngokushesha, ezingavimba i-virus ukungasebenzi. Ubuchwepheshe be-electromagnetic wave busadinga ukuthuthukiswa ukunqoba inkinga yokungasebenzi kahle kwamagciwane e-pathogenic. Ekugcineni, ukumunyisa okuphezulu kwamandla akhanyayo ngama-molecule we-polar maphakathi, njengama-molecule wamanzi, kuphumela ekulahlekelweni kwamandla. Ngaphezu kwalokho, ukusebenza ngempumelelo kwe-SRET kungathintwa izindlela eziningana ezingaziwa ngamagciwane [28]. Umphumela we-SRET futhi ungaguqula leli gciwane ukuvumelanisa nemvelo yalo, okuholela ekumelaneni namagagasi e-electromagnetic [29].
Esikhathini esizayo, ubuchwepheshe be-virus yokungaxhunyiwe kusetshenziswa amagagasi e-electromagnetic kudinga ukwenziwa ngcono. Ucwaningo lwesayensi oluyisisekelo kufanele luhloswe ngalo ukucacisa indlela ye-virus engasebenzi ngamagagasi e-electromagnetic. Isibonelo, indlela yokusebenzisa amandla amagciwane lapho ivezwa amagagasi e-electromagnetic, inqubo eningiliziwe yesenzo se-pathogenic esibulala amagciwane e-pathogenic phakathi kwamagagasi we-electromagnetic phakathi kwamagagasi e-electromagnetic nezinhlobo ezahlukahlukene zamagciwane kufanele acaciswe ngokuhlelekile. Ucwaningo olusetshenzisiwe kufanele lugxile ekutheni ungakuvimbela kanjani ukumuncwa kwemisebe ngokweqile ngama-molecule we-polar, funda umphumela wamagagasi e-electromagnetic ahlukahlukene ama-virus ahlukene kuma-virus ahlukahlukene we-pathogenic, futhi utadishe imiphumela engeyona eye-arrmal yamagagasi e-electrogenic.
Amagagasi e-electromagnetic asephenduke indlela ethembisayo yokungasebenzi kwamagciwane e-pathogenic. Ubuchwepheshe be-Electromagnetic Wave bunezinzuzo zokungcoliswa okuphansi, izindleko eziphansi, kanye ne-virus ephezulu yegciwane elingasebenzi kahle, okungakunqoba ukulinganiselwa kobuchwepheshe bendabuko yendabuko yegciwane le-anti-virus. Kodwa-ke, kudingeka ucwaningo olwengeziwe ukunquma amapharamitha we-electromagnetic wave technology futhi acacise indlela ye-accoctivation yegciwane.
Umthamo othile we-electromagnetic radiation ingabhubhisa ukwakheka kanye nomsebenzi wamagciwane amaningi we-pathogenic. Ukusebenza kahle kwegciwane elingaphakathi kuhlobene kakhulu nemvamisa, ukuqina kwamandla, nesikhathi sokuvezwa. Ngaphezu kwalokho, izindlela ezingaba khona zifaka imiphumela eshisayo, ye-athermal, kanye nemiphumela yokudluliselwa kwamandla. Uma kuqhathaniswa nobuchwepheshe bendabuko be-antiviral, i-virus ye-electromagnetic wave i-i-Intactivation inezinzuzo zokulula, ukusebenza kahle okuphezulu nokungcoliswa okuphansi. Ngakho-ke, i-virus ye-virus ye-electromagnetic yave-medioted i-IntaccIvation ibe yindlela ethembisayo ye-antiviral yezinhlelo zokusebenza ezizayo.
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