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Ama-virus (amagciwane e-Biological) ayizinto eziphilayo ezingezona ezeseli ezibonakala ngobukhulu obuncane, isakhiwo esilula, kanye nokuba khona kohlobo olulodwa kuphela lwe-nucleic acid (i-DNA noma i-RNA). Kumelwe afake amagciwane kumaseli aphilayo ukuze azalane futhi ande. Lapho ehlukaniswa namaseli awo, ama-virus aba yizinto zamakhemikhali ezingenayo imisebenzi yokuphila futhi azikwazi ukuziphindaphinda ngokuzimela. Amandla awo okuzalana, ukubhala, kanye nokuhumusha konke kwenziwa ngaphakathi kweseli elizalana. Ngakho-ke, ama-virus akha isigaba sezinto eziphilayo esiyingqayizivele esinezici zamakhemikhali zama-molecule kanye nezici eziyisisekelo zezinto eziphilayo; akhona njengezinhlayiya ezithelelanayo zangaphandle kanye nezinhlaka zofuzo ezizalana ngaphakathi kweseli.
Amagciwane ngamanye mancane kakhulu, kanti iningi lawo litholakala kuphela ngaphansi kwe-microscope ye-electron. Ama-poxvirus amakhulu kunawo wonke, angaba ama-nanometer angu-300, kanti amancane kunawo wonke, ama-circovirus, angaba ama-nanometer angu-17 ngobukhulu. Kuyaziwa kabanzi ukuthi amagciwane amaningi abeka usongo olukhulu empilweni nasekuphileni kwabantu, njenge-coronavirus entsha, igciwane le-hepatitis B (HBV), kanye negciwane le-human immunodeficiency virus (HIV). Kodwa-ke, amanye amagciwane ebhayoloji nawo anikeza izinzuzo ezithile kubantu. Isibonelo, ama-bacteriophages angasetshenziswa ukwelapha izifo ezithile zamagciwane, ikakhulukazi lapho ebhekene nama-superbug lapho ama-antibiotic amaningi engasebenzi khona.
Ngokuphazima kweso, sekudlule iminyaka emithathu kusukela kwaqala ubhubhane lwe-COVID-19. Kodwa-ke, ukuhlolwa kwe-nucleic acid kudlulela ngale kokuthola i-coronavirus entsha. Ngale kwe-COVID-19, ukuhlolwa kwe-nucleic acid kusebenza njengendinganiso yegolide yokuthola ngokushesha nangokunembile amagciwane amaningi, kuvikele impilo yethu njalo. Ngaphambi kokuhlolwa kwe-nucleic acid, ukuthola ama-virtual nucleic acid asezingeni eliphezulu, ahlanzwe kakhulu kubalulekile ukuqinisekisa ukunemba kwezinqubo zokuxilonga ezilandelayo.
Isingeniso Somkhiqizo
Ukubuka konke komkhiqizo:
Le khithi ihlanganisa ubuhlalu be-superparamagnetic kanye nama-buffer okukhipha alungiselelwe kusengaphambili, anikeza ukulula, ukucubungula okusheshayo, isivuno esikhulu, kanye nokuzala kabusha okuhle kakhulu. I-DNA/RNA ye-genomic ephumelelayo ayinayo iphrotheni, i-nuclease, noma okunye ukuphazamiseka okungcolisayo, okufanelekela i-PCR/qPCR, i-NGS, nezinye izinhlelo zokusebenza ze-molecular biology. Uma kuhlanganiswe ne-I-BigFishi-nucleic acid extractor esekelwe kuma-magnetic bead, ifaneleka kakhulu ekukhipheni ngokuzenzakalelayo amavolumu amakhulu esampula.
Izici Zomkhiqizo:
Ukusetshenziswa Kwesampula Ebanzi: Kufanelekela ukukhishwa kwe-nucleic acid emithonjeni ehlukahlukene ye-DNA/RNA yegciwane, okuhlanganisa i-HCV, i-HBV, i-HIV, i-HPV, kanye namagciwane abangela izifo ezilwaneni.
Okusheshayo Nokulula: Ukusebenza okulula okudinga ukwengeza amasampula kuphela ngaphambi kokucutshungulwa komshini, kususa isidingo sezinyathelo eziningi zokuhlanganisa. Kuhambisana nezikhiphi ze-nucleic acid ezizinikele, ezifanele kakhulu ukucutshungulwa kwamasampula aphezulu.
Ukunemba Okuphezulu: Uhlelo oluhlukile lwe-buffer luqinisekisa ukuphindaphindeka okuhle kakhulu lapho kukhishwa amasampula egciwane anokuhlushwa okuncane.
Izinsimbi Ezihambisanayo:
Uchungechunge lweBigFish BFEX-32E/BFEX-32/BFEX-96E
Isikhathi sokuthunyelwe: Septhemba-04-2025
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