I-Revolution in Molecular Diagnostics: Iqhaza lamakhithi e-Nucleic Acid Extraction

Ukubaluleka kokuxilonga okuthembekile kwamangqamuzana emkhakheni othuthukayo wesayensi yezempilo nokunakekelwa kwezempilo akunakugcizelelwa. I-Bigfish ihamba phambili kulokhu kuguquguquka, inkampani ezibophezele ekugxileni kubuchwepheshe obuyisisekelo nokwakha umkhiqizo wakudala kulo mkhakha. Ngomgomo wokuhlinzeka amakhasimende ngemikhiqizo ethembekile yokuxilonga amangqamuzana, i-Bigfish izimisele ukunamathela kusitayela somsebenzi esiqinile nesisebenzayo futhi isungule izinto ezintsha ngenkuthalo ukuze ihlangabezane nezidingo zemboni.

Enye yezingxenye ezibalulekile zokuxilongwa kwamangqamuzana ukukhishwa kwe-nucleic acid, okubalulekile ezinhlobonhlobo zezicelo, okuhlanganisa ukuhlolwa kofuzo, ukuxilongwa kwezifo, nocwaningo. Imishini yokukhipha i-Nucleic acid idlala indima ebalulekile kule nqubo, ivumela ososayensi nochwepheshe bezokunakekelwa kwempilo ukuthi bahlukanise ngokunembile nangempumelelo i-DNA ne-RNA kumasampula ezinto eziphilayo. I-Bigfish ibona isimo esibucayi salezi zinsiza futhi ikwenze kwaba yinto ehamba phambili ukuthuthukisa izixazululo zekhwalithi ephezulu zokukhipha i-nucleic acid ezihlangabezana nezidingo zamalabhorethri esimanje.

Ukubaluleka kwekhithi yokukhipha i-nucleic acid kusekwazini kwabo ukuhlinzeka ngama-nucleic acid amsulwa futhi angaguquki, abalulekile ekusetshenzisweni komfula okuphansi njenge-PCR (i-polymerase chain reaction), ukulandelana, kanye ne-cloning. Izinga lama-nucleic acid akhishiwe lithinta ngokuqondile ukunemba nokuthembeka kwemiphumela etholwe kulezi zinhlelo zokusebenza. Ngakho-ke, ukutshala imali kukhithi yokukhipha i-nucleic acid ehloniphekile kubalulekile kunoma iyiphi ilabhorethri okuhloswe ngayo ukuthola imiphumela engaguquki futhi ekwazi ukukhiqizwa kabusha.

I-Bigfish'samakhithi e-nucleic acid extractionaklanywe kucatshangelwa umsebenzisi, ahlinzeka ngokugeleza komsebenzi ngendlela elula futhi ephumelelayo enciphisa ukusebenza ngesikhathi kuyilapho kukhulisa isivuno nobumsulwa. Amakhithi afanele izinhlobo zamasampula ahlukahlukene, okuhlanganisa igazi, izicubu, nesiko lamaseli, okuwenza abe amathuluzi ahlukahlukene ocwaningo oluhlukahlukene kanye nezicelo zomtholampilo. Ngokugxila kubuchwepheshe obuyisisekelo, i-Bigfish iqinisekisa ukuthi izinsiza zayo zokukhipha zihlanganisa intuthuko yakamuva kubhayoloji yamangqamuzana, ihlinzeka amakhasimende ngezixazululo ezisezingeni eliphezulu ezithuthukisa amakhono awo okucwaninga.

Ukwengeza, ukuzibophezela kwe-Bigfish ekusunguleni kudlulela ngalé kokuthuthukisa amakhithi okukhipha i-nucleic acid. Inkampani ibambisana ngenkuthalo nabacwaningi kanye nabasebenzi bezempilo ukuze baqonde izidingo nezinselelo zabo, okubavumela ukuthi bahlanganise imikhiqizo yabo ngendlela efanele. Le ndlela yokugxila kumakhasimende ayigcini nje ngokukwakha ukwethembana, kodwa futhi ibeka i-Bigfish isikhundla njengomholi ekuhlonzweni kwamangqamuzana.

Njengoba isidingo sokuxilonga amangqamuzana siqhubeka sikhula ngokuthuthuka kwemithi yomuntu siqu kanye nokusabalala okwandayo kwezifo zofuzo, indima yekhithi yokukhipha i-nucleic acid izoba bucayi kakhulu. I-Bigfish ikulungele ukuhlangabezana nalesi sidingo ngokunikeza izixazululo ezinokwethenjelwa, ezisebenza kahle ezenza abacwaningi nodokotela bakwazi ukwenza izinqumo ezisekelwe kudatha enembile.

Kafushane, amakhithi okukhipha i-nucleic acid ayithuluzi elibalulekile emkhakheni wokuxilongwa kwamangqamuzana, futhi i-Bigfish ihamba phambili kulokhu kuqanjwa kabusha. Ngomgomo wokwakha umkhiqizo wakudala, i-Bigfish izimisele ukuhlinzeka amakhasimende ngemikhiqizo yokuxilonga yamangqamuzana esezingeni eliphezulu enomoya wokusebenza kanzima kanye nokusungula izinto ezintsha. Njengoba inkampani iqhubeka nokukhula futhi yandise ububanzi bemikhiqizo yayo, ihlezi iqinile ekuzibophezeleni kwayo ekubeni inkampani esezingeni lomhlaba emkhakheni wesayensi yezempilo nokunakekelwa kwezempilo. Ngokukhetha izinsiza zokukhipha i-nucleic acid ye-Bigfish, amalabhorethri angaqinisekisa ukuthi ahlonyiswe ngamathuluzi angcono kakhulu okuqhubekisela phambili ucwaningo lwawo nokuthuthukisa imiphumela yesiguli.