Ukusheshisa ukuxilongwa kwezifo okuthembekile

Ukubambezeleka kokuxilongwa kwezifo ezithathelanayo beka inani labantu abasabalele engcupheni emhlabeni wethu womhlaba, ikakhulukazi ngama-zoonotic pathogens asakazwa phakathi kwezilwane nabantu. Ilinganiselwa ku-75% yamagciwane asanda kutholwa abantu abangama-30 aqoshwe eminyakeni engama-30 edlule ngo-2008 asuka ezilwaneni, ngokombiko we-WHO okhishwe ngo-2021.

"Ithimba lethu lizinikele ekunqobeni izinselelo zokuklama ukuxilonga ukuze kusetshenziswe isidingo sokuxilonga sejubane le-POCT nokufinyeleleka kokubili kwe-IVD (in-vitro) kanye ne-non-IVD, "kusho uLianyi Xie, owasungula i-Hangzhou Bigfish Bio-tech Co., Ltd, ngo-2017. "Izivivinyo zethu zokunakekelwa (i-POCT) zenzelwe ukusebenza ngokushesha ezimweni ezinomkhawulo wezinsiza, ngenkathi i-catering. ngezifo ezihlukahlukene.”

I-Bigfish's POCTs yakhelwe ukuvikela ukuphepha kokudla, kanye nempilo yemfuyo nezilwane ezihambisana nazo, ikakhulukazi uma kucatshangelwa inani elikhulayo laseShayina labanikazi bezilwane ezifuywayo.

Ukugunyazwa kwedizayini esheshayo ye-POCT, u-Xie wachaza, kufanele kunyathele ibhalansi phakathi kokuqanjwa kabusha nokugxila kubuchwepheshe bokukhulisa bendabuko nobuthembekile, obusekelwe ku-polymerase chain reaction (PCR), ukuze kutholwe amanani amaminithi ama-nucleic acid avela kumidiya eyinkimbinkimbi.

Cabanga ngokugqashuka kwe-African swine fever (ASF) e-China, okuyikhaya lemakethe enkulu kunazo zonke emhlabeni yokukhiqiza inyama yengulube. Ngo-2019, i-ASF yabangela ukufa kwezingulube ezingaphezu kwezigidi ezingama-43, futhi cishe ama-dollar ayizigidi eziyizinkulungwane eziyi-111 ekulahlekeni. Ukusheshisa imiklamo ye-POCT kuncike ekusebenzelaneni eduze nezikhungo zezemfundo nezikahulumeni, kanye nempendulo evela kubasebenzisi, njengabafuyi abakhulu bezingulube base-China.

“Ukunemba nokuzwela ngokuhambisana nezilungiselelo zaselabhorethri, ngisho nasemapulazini amancane akude, kubalulekile kumathuluzi ethu, enziwa ukuthi athengeke futhi asebenziseke kalula kunoma yimuphi umhlambi wezingulube,” kuchaza u-Xie.

Umsebenzi we-Bigfish ekuvimbeleni nasekuqedeni izifo ezweni lonke udlulela naku-brucellosis, esesiyisifo esivame kakhulu emhlabeni wonke, kanye nezifo ezihambisana nezilwane.

I-Bigfish isisize ngokushesha i-POCT ezikhungweni zezilwane ezingaba ngu-4,000 kulo lonke elase-China. UShuilin Zhu, usihlalo weZhejiang Small Animal Protection Association, wengeze ngokuthi ubuchwepheshe benkampani bezilwane.

ukufuywa kanye nokunakekelwa kwezilwane ezifuywayo akugcini nje ukwandisa ukusebenza kahle kokuvimbela nokulawula, kodwa futhi kuthuthukisa kakhulu inhlalakahle yezilwane.

Ukunika amandla idizayini ehlangene ngaphandle kwezindleko ezinkulu kubasebenzisi kungenye into ebalulekile ekwakhiweni nasekukhiqizeni ukuhlolwa kwabo kofuzo. I-molecular diagnostic assay i-GeNext ayinkulu kunebhodlela lamanzi, futhi inesisindo esingamakhilogremu angu-2. Ifaka ama-chips e-mesofluidic nama-microfluidic ashintsha ngokuzenzakalelayo izinyathelo ezikhandlayo kusukela ekukhishweni kwe-nucleic acid, ukukhulisa izakhi zofuzo kuya ekulayishweni nasekuhlaziyweni kwedatha yesikhathi sangempela.

Ivalwe ngokugcwele ukuze kugwenywe ukungcola okungaba khona kwe-aerosol, i-GeNext 2.0 manje ekukhiqizweni ngobuningi ingavumela ukuphuma kwesampula kukhuphuke ukusuka ku-1 kuye ku-16 umzuliswano ngamunye, ukulandelana okuhlosiwe kunwetshwe ukusuka ku-5 ukuya ku-25 ngokugijima ngakunye, ngaphandle kwesikhathi esengeziwe noma izindleko.

"Imiklamo yethu ye-GeNext 3.0 izophinde inciphise isikhathi, ithuthuke ngama-chips asekelwe ku-silicon, futhi ihlanganise nobuchwepheshe bokulandelana obufana nokulandelana kwe-nanopore ukuze uthole umongo obanzi womtholampilo ekuhlolweni kokubeletha kanye nokutholwa komdlavuza kusenesikhathi," kusho u-Xie. "Imiklamo yethu ye-POCT ngelinye ilanga ingasetshenziswa yinoma ngubani, noma kuphi ngaphandle kokubheka izindleko."