Ukusheshisa ukuxilongwa kwezifo okuthembekile

Ukuxilongwa kwezifo ezithathelwanayo okubambezelekile kubeka inani labantu abaningi engcupheni emhlabeni wethu womhlaba wonke, ikakhulukazi ngezifo ezibangelwa yizilwane ezidluliselwa phakathi kwezilwane nabantu. Kulinganiselwa ukuthi ama-75% ezifo ezibangelwa yizilwane ezisanda kutholakala ezingama-30 ezibhalwe eminyakeni engama-30 edlule ngo-2008 zivela ezilwaneni, ngokusho kombiko we-WHO owakhishwa ngo-2021.

"Ithimba lethu lizinikele ekunqobeni izinselele zokuklama ukuxilonga ukuze kuhlangatshezwane nesidingo sokuxilonga sejubane le-POCT kanye nokufinyeleleka kuzo zombili i-IVD (ngaphakathi kwe-vitro) kanye ne-non-IVD,” kusho uLianyi Xie, owasungula i-Hangzhou Bigfish Bio-tech Co., Ltd, ngo-2017. “Ukuhlolwa kwethu kokunakekelwa (i-POCT) kwenzelwe ukusebenza ngokushesha ezimweni ezilinganiselwe, kuyilapho kubhekelelwa izinhlobo ezahlukene zezifo.”

Ama-POCT e-Bigfish aklanyelwe ukuvikela ukuphepha kokudla, kanye nempilo yemfuyo kanye nezilwane ezihambisana nayo, ikakhulukazi uma kucatshangelwa inani elikhulayo labanikazi bezilwane ezifuywayo eShayina.

Ukuvunyelwa okusheshayo komklamo we-POCT, kuchaza uXie, kumele kuhambisane nebhalansi enhle phakathi kokusungula izinto ezintsha kanye nokugxila kubuchwepheshe bendabuko nobethembekile bokukhulisa, obusekelwe ku-polymerase chain reaction (PCR), ukuthola inani elincane lama-nucleic acid avela ezindabeni eziyinkimbinkimbi.

Cabanga ngokuqubuka komkhuhlane wezingulube wase-Afrika (i-ASF) eShayina, okuyikhaya lemakethe enkulu kunazo zonke yokukhiqizwa nokusetshenziswa kwezingulube emhlabeni. Ngo-2019, i-ASF yabangela ukufa kwezingulube ezingaphezu kwezigidi ezingu-43, kanye nokulahlekelwa okulinganiselwa ku-$US 111 billion. Ukuthuthukisa imiklamo ye-POCT kuncike ekubambisaneni okuseduze nezinhlangano zezemfundo kanye nohulumeni, kanye nempendulo evela kubasebenzisi, njengabafuyi bezingulube abakhulu baseShayina.

“Ukunemba kanye nokuzwela okuhambisana nezindawo zelebhu, ngisho nasemapulazini amancane akude, kubalulekile kuma-kit ethu, enziwe angabizi futhi alula ukuwasebenzisa kunoma yimuphi umhlambi wezingulube,” kuchaza uXie.

Umsebenzi we-Bigfish wokuvimbela nokuqeda izifo ezweni lonke udlulela naku-brucellosis, okusalokhu kuyisifo esivame kakhulu se-zoonotic emhlabeni jikelele, kanye nezifo ezilwaneni ezihambisana nazo.

I-Bigfish ithuthukise i-POCT ngokushesha ezikhungweni zezilwane ezingaba ngu-4,000 kulo lonke elaseShayina. UShuilin Zhu, usihlalo we-Zhejiang Small Animal Protection Association, wanezela ukuthi ubuchwepheshe benkampani bezilwane

Ukunakekela izilwane ezifuywayo kanye nokufuywa akugcini nje ngokwandisa ukusebenza kahle kokuvimbela nokulawula, kodwa futhi kuthuthukisa kakhulu inhlalakahle yezilwane.

Ukunika amandla umklamo omncane ngaphandle kwezindleko ezinkulu kubasebenzisi kungenye into eza kuqala ekwakhiweni nasekukhiqizweni kwezivivinyo zabo zofuzo. Ukuhlolwa kwabo kokuxilongwa kwama-molecule i-GeNext akukhulu kunebhodlela lamanzi, futhi kunesisindo esingamakhilogremu ama-2. Iqukethe ama-chip e-mesofluidic kanye ne-microfluidic azenzakalela izinyathelo ezinzima kusukela ekukhishweni kwe-nucleic acid, ukukhuliswa kofuzo kuya ekulayishweni kwedatha ngesikhathi sangempela kanye nokuhlaziywa.

Ivalwe ngokuphelele ukuze kugwenywe ukungcoliswa okungenzeka kwe-aerosol, i-GeNext 2.0 manje esekukhiqizweni okukhulu ingenza ukuthi ukugeleza kwesampula kukhuphuke kusuka ku-1 kuya ku-16 ngomjikelezo ngamunye, ukulandelana okuqondiwe kwandiswe kusuka ku-5 kuya ku-25 ngokugijima ngakunye, ngaphandle kwesikhathi esengeziwe noma izindleko.

“Imiklamo yethu ye-GeNext 3.0 izoqhubeka nokunciphisa isikhathi, ithuthukise ngama-chip asekelwe ku-silicon, futhi ifake ubuchwepheshe bokulandelana njengokulandelana kwe-nanopore ukuze kube nomongo obanzi wezokwelapha ekuhlolweni kokukhulelwa kanye nokuxilongwa komdlavuza kusenesikhathi,” kusho uXie. “Imiklamo yethu ye-POCT ingasetshenziswa yinoma ubani ngelinye ilanga, noma kuphi ngaphandle kokucabanga ngezindleko.”